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  • TMB and Immunotherapy (MSKCC, Nat Genet 2019): Genomic and survival data from 1661 tumor-normal pairs from 1661 patients with various cancer types sequenced with the MSK-IMPACT assay.

    Description

    This dataset contains summary data visualizations and clinical data from a broad sampling of 1,661 samples of across multiple cancer types showing tumor mutational load and survival following immunotherapy from 1,661 patients. The data was gathered utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes tumor type (based on the opensource OncoTree ontology developed at MSK),...

    Subject
    DNA Mutational Analysis
    Immunotherapy
    Mutation
    Tumor Burden
    Access Rights
    Free to All
  • Tumors with TRK fusions (MSK, 2019): Tumors with TRK fusions based on MSK-IMPACT targeted sequencing.

    Description

    This dataset contains summary data visualizations and clinical data from a broad sampling of tropomyosin receptor kinase (TRK) fusion tumors. The data was gathered utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes tumor type (based on the opensource OncoTree ontology developed at MSK), information about mutated genes, patient demographics, and modality. The data set also...

    Subject
    DNA Mutational Analysis
    Oncogene Proteins, Fusion
    Receptor Protein-Tyrosine Kinases
    Receptor, trkA
    Receptor, trkB
    Receptor, trkC
    Access Rights
    Free to All
  • Mixed cfDNA (MSKCC, 2020): IMPACT sequencing of 229 cell-free DNA (cfDNA) and associated tumor samples with matched normal

    Description

    This dataset contains the summary data visualizations and clinical data of IMPACT sequencing of 229 cell-free DNA (cfDNA) and associated tumor samples with matched normal from 118 patients. Clinical data includes: Cancer Type, Number of Samples Per Patient, Mutation Count, Fraction Genome Altered, Sex, Primary/Metastasis Sample Type, Collaboration Id, Gene Panel, Oncotree Code, Tumor/cfDNA Sample...

    Subject
    Adenocarcinoma
    Adenocarcinoma of Lung
    Breast Neoplasms
    Carcinoma, Ductal, Breast
    Carcinoma, Neuroendocrine
    Carcinoma, Renal Cell
    Carcinoma, Squamous Cell
    Cell-Free Nucleic Acids
    Choriocarcinoma
    Endodermal Sinus Tumor
    Melanoma
    Neoplasms, Germ Cell and Embryonal
    Neoplasms, Squamous Cell
    Neuroendocrine Tumors
    Prostatic Neoplasms
    Seminoma
    Small Cell Lung Carcinoma
    Urinary Bladder Neoplasms
    Access Rights
    Free to All